An immunoaffinity tandem mass spectrometry (iMALDI) assay for detection of Francisella tularensis
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چکیده
منابع مشابه
Development of an immuno tandem mass spectrometry (iMALDI) assay for EGFR diagnosis.
The epidermal growth factor receptor (EGFR) is highly expressed in a variety of tumors, and is therefore an important biomarker for cancer diagnosis and a target for cancer therapy. We have developed a novel peptide-based immuno tandem mass spectrometry (iMALDI) diagnostic assay for highly sensitive, highly specific, and quantitative analysis of EGFR, which we have applied to the detection of t...
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Several real-time PCR approaches to develop field detection for Francisella tularensis, the infectious agent causing tularemia, have been explored. We report the development of a novel qualitative real-time isothermal recombinase polymerase amplification (RPA) assay for use on a small ESEQuant Tube Scanner device. The analytical sensitivity and specificity were tested using a plasmid standard a...
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F rancisella tularensis was first isolated in 1912 from rodents suffering from a plague-like disease in Tulare County, Calif. Subsequently, investigators learned that this small, gram-negative bacterium infects many animal species and is associated with a wide range of diseases. In humans, the bacterium causes a serious, sometimes fatal disease, called tularemia, which is also known as rabbit f...
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Glycosaminoglycans (GAGs) are distributed in the whole body and play a variety of important physiological roles associated with inflammation, growth, coagulation, fibrinolysis, lipolysis, and cell-matrix biology. Accumulation of undegraded GAGs in lysosomes gives rise to a distinct clinical syndrome, mucopolysaccharidoses. Measurement of each specific GAG in a variety of specimens is urgently r...
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ژورنال
عنوان ژورنال: Analytica Chimica Acta
سال: 2007
ISSN: 0003-2670
DOI: 10.1016/j.aca.2007.10.025